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GENE - TERM ANNOTATION REPORT

RGD ID: 1309876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tspan31
Name: tetraspanin 31
Acc ID: DOID:9007071
Term: Hereditary Neoplastic Syndromes
Definition: The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.
Definition Source(s): MESH:D009386
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tspan31 ISOTSPAN31 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary Cancer Syndrome | ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromePMID:17576681 PMID:20668451 PMID:21520333 PMID:23718828 PMID:24728327 PMID:24755471 PMID:25318351 PMID:25741868 PMID:25980754 PMID:26252490 PMID:26467025 PMID:26580448 PMID:27997549 PMID:28166811 PMID:28492532 PMID:29641532 PMID:29917049 PMID:30093976 PMID:30851086 PMID:31159747 PMID:34285288 PMID:35264596 PMID:9536098
Tspan31 ISOTSPAN31 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary Cancer Syndrome | ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromePMID:17576681 PMID:20668451 PMID:21520333 PMID:23718828 PMID:24728327 PMID:24755471 PMID:25318351 PMID:25741868 PMID:25980754 PMID:26252490 PMID:26467025 PMID:27997549 PMID:28166811 PMID:28492532 PMID:29917049 PMID:30093976 PMID:30851086 PMID:31159747 PMID:34285288 PMID:9536098
Tspan31 ISOTSPAN31 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary Cancer Syndrome | ClinVar Annotator: match by term: Hereditary cancer-predisposing syndrome | ClinVar Annotator: match by term: Hereditary neoplastic syndromePMID:17576681 PMID:20668451 PMID:21520333 PMID:23718828 PMID:24728327 PMID:24755471 PMID:25305755 PMID:25318351 PMID:25344691 PMID:25741868 PMID:25980754 PMID:26252490 PMID:26467025 PMID:26580448 PMID:27640074 PMID:27997549 PMID:28166811 PMID:28492532 PMID:29641532 PMID:29917049 PMID:30093976 PMID:30851086 PMID:31159747 PMID:31784493 PMID:32980694 PMID:34285288 PMID:35264596 PMID:36095024 PMID:36243179 PMID:9536098
Tspan31 ISOTSPAN31 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary Cancer Syndrome | ClinVar Annotator: match by term: Hereditary cancer-predisposing syndrome | ClinVar Annotator: match by term: Hereditary neoplastic syndrome | ClinVar Annotator: match by term: Neoplastic Syndromes, HereditaryPMID:17576681 PMID:20668451 PMID:21520333 PMID:23718828 PMID:24728327 PMID:24755471 PMID:25305755 PMID:25318351 PMID:25344691 PMID:25741868 PMID:25980754 PMID:26252490 PMID:26467025 PMID:26580448 PMID:27640074 PMID:27997549 PMID:28166811 PMID:28492532 PMID:29641532 PMID:29917049 PMID:30093976 PMID:30851086 PMID:31159747 PMID:31784493 PMID:32980694 PMID:34285288 PMID:34326862 PMID:35264596 PMID:36095024 PMID:36243179 PMID:9536098
Tspan31 ISOTSPAN31 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary Cancer Syndrome | ClinVar Annotator: match by term: Hereditary cancer-predisposing syndrome | ClinVar Annotator: match by term: Neoplastic Syndromes, HereditaryPMID:20668451 PMID:21520333 PMID:23718828 PMID:24728327 PMID:24755471 PMID:25318351 PMID:25741868 PMID:25980754 PMID:26252490 PMID:26467025 PMID:27997549 PMID:28166811 PMID:28492532 PMID:29917049 PMID:30093976 PMID:31159747
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