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GENE - TERM ANNOTATION REPORT

RGD ID: 1309831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nlrc4
Name: NLR family, CARD domain containing 4
Acc ID: GO:0072557
Term: IPAF inflammasome complex
Definition: An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.
Definition Source(s): GOC:add, GOC:BHF, GOC:vp, PMID:20303873
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrc4part_ofISONlrc4 (Mus musculus)1624291RGD MGI:5289703 PMID:21874021 MGI:5444805 PMID:22885697

MGI:5289703 MGI:5444805 PMID:21874021 PMID:22885697
Nlrc4part_ofISSUniProtKB:Q3UP241600115UniProtGO_REF:0000024

GO_REF:0000024
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