GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tfeb | affects localization | ISO | Tfeb (Mus musculus) | 6480464 | CTD | Arsenic Trioxide affects the localization of TFEB protein | PMID:33462182 | Tfeb | increases expression | ISO | TFEB (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of TFEB mRNA | PMID:29307831 | Tfeb | multiple interactions | ISO | TFEB (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of TFEB protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TFEB mRNA]; Arsenic Trioxide results in decreased phosphorylation of and affects the localization of TFEB protein; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of CTSB mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of UVRAG mRNA] | PMID:29307831 | Tfeb | multiple interactions | ISO | Tfeb (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of TFEB protein]; TFEB protein affects the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG12 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein] | PMID:33462182 | | ||||||||||||||||||||||
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