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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309465
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Exo1
Name: exonuclease 1
Acc ID: CHEBI:92658
Term: kenpaullone
Definition: An indolobenzazepine that is paullone in which the hydrogen at position 9 is replaced by a bromo substituent. It is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3beta (GSK3beta).
Chemical ID: MESH:C119620
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Exo1decreases expressionEXP 6480464CTDkenpaullone results in decreased expression of EXO1 mRNAPMID:17993264
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