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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309427
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tubb2b
Name: tubulin, beta 2B class IIb
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tubb2bincreases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of TUBB2B mRNAPMID:21839799
Tubb2baffects methylationISOTUBB2B (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of TUBB2B promoterPMID:27901495
Tubb2bdecreases expressionISOTubb2b (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of TUBB2B mRNAPMID:19770486
Tubb2bdecreases methylationISOTUBB2B (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of TUBB2B 3' UTRPMID:27901495
Tubb2bincreases expressionISOTubb2b (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of TUBB2B mRNAPMID:22228805
Tubb2bincreases methylationISOTUBB2B (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of TUBB2B exonPMID:27901495
Tubb2bmultiple interactionsISOTubb2b (Mus musculus)6480464CTDAHR protein affects the reaction [Benzo(a)pyrene affects the expression of TUBB2B mRNA]PMID:22228805
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