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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309412
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Creld1
Name: cysteine-rich with EGF-like domains 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Creld1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CRELD1 mRNAPMID:30816183 PMID:32528016 PMID:34947998
Creld1increases expressionEXP 6480464CTDbisphenol A results in increased expression of CRELD1 mRNAPMID:25181051
Creld1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CRELD1 mRNA; [bisphenol A co-treated with tributyltin] results in increased expression of CRELD1 mRNAPMID:31129395 PMID:36041667
Creld1increases expressionISOCRELD1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of CRELD1 proteinPMID:34186270
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