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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309229
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agpat2
Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agpat2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of AGPAT2 mRNAPMID:21215274
Agpat2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of AGPAT2 mRNAPMID:33387578
Agpat2affects expressionISOAGPAT2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of AGPAT2 mRNAPMID:22298810
Agpat2affects expressionISOAgpat2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of AGPAT2 mRNAPMID:21570461 PMID:26377647
Agpat2decreases expressionISOAgpat2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AGPAT2 mRNAPMID:28213091 PMID:28238261 PMID:28922406
Agpat2increases expressionISOAGPAT2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of AGPAT2 mRNAPMID:20106945 PMID:21632981
Agpat2multiple interactionsISOAgpat2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to AGPAT2 gene]PMID:28213091
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