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GENE - TERM ANNOTATION REPORT

RGD ID: 1309063
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stat6
Name: signal transducer and activator of transcription 6
Acc ID: GO:0048289
Term: isotype switching to IgE isotypes
Definition: The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.
Definition Source(s): ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat6acts_upstream_ofISOStat6 (Mus musculus)1624291RGDMGI:107187 PMID:10490661

PMID:10490661
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