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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncoa1
Name: nuclear receptor coactivator 1
Acc ID: CHEBI:50648
Term: 9-cis-retinoic acid
Definition: A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID: MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncoa1multiple interactionsISONCOA1 (Homo sapiens)6480464CTD[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Alitretinoin] promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]; [Alitretinoin co-treated with NCOA1 protein] results in increased activity of RXRB protein; Alitretinoin promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]PMID:17223708 PMID:22227104
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