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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308825
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psmc6
Name: proteasome 26S subunit, ATPase 6
Acc ID: CHEBI:26523
Term: reactive oxygen species
Definition: Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Chemical ID: MESH:D017382
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmc6decreases expressionISOPsmc6 (Mus musculus)6480464CTDReactive Oxygen Species results in decreased expression of PSMC6 mRNAPMID:12470298
Psmc6multiple interactionsISOPsmc6 (Mus musculus)6480464CTDButylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of PSMC6 mRNA]; Butylated Hydroxytoluene inhibits the reaction [Reactive Oxygen Species results in decreased expression of PSMC6 mRNA]PMID:12470298
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