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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308676
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd3b1
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Acc ID: CHEBI:82436
Term: decabromodiphenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines.
Chemical ID: MESH:C010902
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd3b1decreases expressionISOHsd3b1 (Mus musculus)6480464CTDdecabromobiphenyl ether results in decreased expression of HSD3B1 mRNA; decabromobiphenyl ether results in decreased expression of HSD3B1 proteinPMID:26602377 PMID:30300726 PMID:31132478
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