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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308574
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Flrt2
Name: fibronectin leucine rich transmembrane protein 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Flrt2increases expressionEXP 6480464CTDbisphenol A results in increased expression of FLRT2 mRNAPMID:29097150 PMID:30816183 PMID:33296240
Flrt2affects methylationISOFLRT2 (Homo sapiens)6480464CTDbisphenol A affects the methylation of FLRT2 genePMID:31601247
Flrt2increases expressionISOFLRT2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of FLRT2 mRNAPMID:29275510
Flrt2increases expressionISOFlrt2 (Mus musculus)6480464CTDbisphenol A results in increased expression of FLRT2 mRNAPMID:30951980
Flrt2multiple interactionsISOFLRT2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of FLRT2 gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FLRT2 mRNAPMID:28628672 PMID:31601247
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