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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rai1
Name: retinoic acid induced 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rai1affects splicingEXP 6480464CTDValproic Acid affects the splicing of RAI1 mRNAPMID:29427782
Rai1affects expressionISORAI1 (Homo sapiens)6480464CTDValproic Acid affects the expression of RAI1 mRNAPMID:25979313
Rai1decreases expressionISORAI1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of RAI1 mRNAPMID:23527032 PMID:28001369
Rai1increases methylationISORAI1 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of RAI1 genePMID:29154799
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