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GENE - TERM ANNOTATION REPORT

RGD ID: 1308488
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp8b1
Name: ATPase phospholipid transporting 8B1
Acc ID: DOID:1852
Term: intrahepatic cholestasis
Definition: A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver. (DO)
Definition Source(s): https://medlineplus.gov/ency/article/000215.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp8b1susceptibilityISOATP8B1 (Homo sapiens)1599397RGD  
Atp8b1 ISOATP8B1 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:18379143
Atp8b1 ISOATP8B1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Progressive intrahepatic cholestasisPMID:14988830 PMID:15239083 PMID:19731236 PMID:19918981 PMID:20232290 PMID:22525741 PMID:25741868 PMID:26382629 PMID:26858187 PMID:26879107 PMID:28492532 PMID:31450232 PMID:33437900 PMID:33666275 PMID:34016879 PMID:5807632 PMID:9500542 PMID:9918928
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