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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308188
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Upp2
Name: uridine phosphorylase 2
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Upp2increases expressionEXP 6480464CTDAcetaminophen results in increased expression of UPP2 mRNAPMID:32479839
Upp2affects expressionISOUpp2 (Mus musculus)6480464CTDAcetaminophen affects the expression of UPP2 mRNAPMID:17562736
Upp2decreases expressionISOUPP2 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of UPP2 mRNAPMID:26690555
Upp2increases expressionISOUPP2 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of UPP2 mRNAPMID:29067470
Upp2multiple interactionsISOUpp2 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of UPP2 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of UPP2 mRNA]PMID:17585979
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