GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2c79 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of CYP2C8 mRNA | PMID:25181051 | Cyp2c79 | decreases activity | ISO | CYP2C8 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased activity of CYP2C8 protein | PMID:10784435 | Cyp2c79 | increases glutathionylation | ISO | CYP2C8 (Homo sapiens) | 6480464 | CTD | CYP2C8 protein results in increased glutathionylation of bisphenol A; CYP2C8 protein results in increased glutathionylation of bisphenol A metabolite | PMID:23470418 | Cyp2c79 | increases hydroxylation | ISO | CYP2C8 (Homo sapiens) | 6480464 | CTD | CYP2C8 protein results in increased hydroxylation of bisphenol A; CYP2C8 protein results in increased hydroxylation of bisphenol A metabolite | PMID:23470418 | |
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