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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308041
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfrsf10b
Name: TNF receptor superfamily member 10b
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf10bincreases expressionISOTNFRSF10A (Homo sapiens)6480464CTDresveratrol results in increased expression of TNFRSF10A mRNA; resveratrol results in increased expression of TNFRSF10A proteinPMID:17636462 PMID:19846903 PMID:21179458 PMID:21209944 PMID:22406996
Tnfrsf10bincreases localizationISOTNFRSF10A (Homo sapiens)6480464CTDresveratrol results in increased localization of TNFRSF10A proteinPMID:19561642
Tnfrsf10bmultiple interactionsISOTNFRSF10A (Homo sapiens)6480464CTD[Benzo(a)pyrene co-treated with resveratrol] results in increased expression of TNFRSF10A mRNA; FOXO1 protein affects the reaction [resveratrol results in increased expression of TNFRSF10A protein]; FOXO3 protein affects the reaction [resveratrol results in increased expression of TNFRSF10A protein]; FOXO4 protein affects the reaction [resveratrol results in increased expression of TNFRSF10A protein]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of TNFRSF10A mRNA]; resveratrol promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of TNFRSF10A protein]PMID:21179458 PMID:23452621 PMID:24289642
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