GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cldn4 | increases expression | EXP | | 6480464 | CTD | Sodium Chloride results in increased expression of CLDN4 mRNA; Sodium Chloride results in increased expression of CLDN4 protein | PMID:23816505 | Cldn4 | multiple interactions | EXP | | 6480464 | CTD | [[SP1 protein co-treated with JUN protein] binds to CLDN4 promoter] promotes the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; diphenyleneiodonium inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; diphenyleneiodonium inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; Glutathione inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; U 0126 inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] | PMID:23816505 | |
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