GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp1 | increases expression | ISO | MMP1 (Homo sapiens) | 6480464 | CTD | Histamine results in increased expression of MMP1 mRNA | PMID:17656145 PMID:9856766 | Mmp1 | increases secretion | ISO | MMP1 (Homo sapiens) | 6480464 | CTD | Histamine results in increased secretion of MMP1 protein | PMID:17656145 | Mmp1 | multiple interactions | ISO | MMP1 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Histamine results in increased secretion of MMP1 protein]; EGFR protein affects the reaction [Histamine results in increased secretion of MMP1 protein]; Famotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]; Famotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein]; RTKI cpd inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]; RTKI cpd inhibits the reaction [Histamine results in increased secretion of MMP1 protein] | PMID:17656145 | | ||||||||||||||||||||||
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