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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307895
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wee1
Name: WEE1 G2 checkpoint kinase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wee1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of WEE1 mRNAPMID:22298810
Wee1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of WEE1 mRNAPMID:21215274 PMID:32109520 PMID:33387578
Wee1affects expressionISOWee1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of WEE1 mRNAPMID:21570461 PMID:28922406
Wee1multiple interactionsISOWee1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to WEE1 promoter]PMID:19654925
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