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GENE - TERM ANNOTATION REPORT

RGD ID: 1307403
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bmi1
Name: BMI1 proto-oncogene, polycomb ring finger
Acc ID: GO:0031507
Term: heterochromatin formation
Definition: An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
Definition Source(s): PMID:25192661, PMID:33827924
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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