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RGD ID: 1307295
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rabgef1
Name: RAB guanine nucleotide exchange factor 1
Acc ID: GO:0060368
Term: regulation of Fc receptor mediated stimulatory signaling pathway
Definition: Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Definition Source(s): GOC:dph, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IEAUniProtKB:Q9JM13, ensembl:ENSMUSP000000263901600115EnsemblGO_REF:0000107

 ISORGD:13164051624291RGD MGI:MGI:3050742, MGI:MGI:3834538, PMID:15235600, PMID:17341663
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.