GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsdmd | increases cleavage | ISO | GSDMD (Homo sapiens) | 6480464 | CTD | Glucose results in increased cleavage of GSDMD protein | PMID:35607288 | Gsdmd | increases expression | ISO | GSDMD (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of GSDMD mRNA; Glucose results in increased expression of GSDMD protein | PMID:37473909 | Gsdmd | increases expression | ISO | Gsdmd (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of GSDMD mRNA | PMID:34212273 | Gsdmd | multiple interactions | ISO | GSDMD (Homo sapiens) | 6480464 | CTD | loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [Glucose results in increased expression of GSDMD protein]; MIR200C mRNA affects the reaction [Glucose results in increased cleavage of GSDMD protein]; SLC30A7 protein affects the reaction [MIR200C mRNA affects the reaction [Glucose results in increased cleavage of GSDMD protein]] | PMID:35607288 PMID:37473909 | Gsdmd | multiple interactions | ISO | Gsdmd (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of and results in increased cleavage of GSDMD protein; GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein]; GSDMD protein affects the reaction [Glucose results in increased secretion of IL1B protein]; Hirudins inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of GSDMD protein]; IRF2 protein affects the reaction [Glucose results in increased expression of and results in increased cleavage of GSDMD protein]; IRF2 protein affects the reaction [Glucose results in increased expression of GSDMD mRNA] | PMID:34212273 | |
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