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GENE - TERM ANNOTATION REPORT

RGD ID: 1307140
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sptlc1
Name: serine palmitoyltransferase, long chain base subunit 1
Acc ID: GO:0005783
Term: endoplasmic reticulum
Definition: The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sptlc1located_inISOSPTLC1 (Homo sapiens) or UniProtKB:O15269-11624291RGD GO_REF:0000052
Sptlc1is_active_inIBAMGI:1099431 or PANTHER:PTN000343996 or SGD:S000004911 or TAIR:locus:2115350 or UniProtKB:O15269 or UniProtKB:Q580D01600115GO_CentralGO_REF:0000033

GO_REF:0000033
Sptlc1located_inIEAPANTHER:PTHR13693:SF21600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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