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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306931
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc30a5
Name: solute carrier family 30 member 5
Acc ID: CHEBI:88217
Term: N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine
Definition: An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Chemical ID: MESH:C044387
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc30a5decreases expressionISOSLC30A5 (Homo sapiens)6480464CTDN,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A5 mRNAPMID:17234632 PMID:19720134
Slc30a5increases expressionISOSLC30A5 (Homo sapiens)6480464CTDN,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC30A5 mRNAPMID:15276077
Slc30a5multiple interactionsISOSLC30A5 (Homo sapiens)6480464CTD[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A] results in decreased expression of SLC30A5 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in decreased expression of SLC30A5 mRNAPMID:19720134
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