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GENE - TERM ANNOTATION REPORT

RGD ID: 1306918
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cops7b
Name: COP9 signalosome subunit 7B
Acc ID: GO:0008180
Term: COP9 signalosome
Definition: A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
Definition Source(s): PMID:11019806, PMID:12186635, PMID:14570571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cops7bpart_ofISOCOPS7B (Homo sapiens)1624291RGD PMID:18850735

PMID:18850735
Cops7bpart_ofIBAFB:FBgn0028836 or PANTHER:PTN000394350 or UniProtKB:Q00648 or UniProtKB:Q9H9Q2 or UniProtKB:Q9UBW8 or dictyBase:DDB_G02712821600115GO_CentralGO_REF:0000033

GO_REF:0000033
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