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GENE - TERM ANNOTATION REPORT

RGD ID: 1306853
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Traf6
Name: TNF receptor associated factor 6
Acc ID: GO:0042088
Term: T-helper 1 type immune response
Definition: An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
Definition Source(s): GOC:add, ISBN:0781735149
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Traf6acts_upstream_of_or_withinISOTraf6 (Mus musculus)1624291RGDMGI:2678775 PMID:14499111

PMID:14499111
Traf6involved_inIEAUniProtKB:P70196 or ensembl:ENSMUSP000000049491600115EnsemblGO_REF:0000107

GO_REF:0000107
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