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GENE - TERM ANNOTATION REPORT

RGD ID: 1306764
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdelr1
Name: KDEL endoplasmic reticulum protein retention receptor 1
Acc ID: GO:0006621
Term: protein retention in ER lumen
Definition: The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
Definition Source(s): ISBN:0716731363, PMID:12972550
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdelr1involved_inIBAFB:FBgn0267330 or PANTHER:PTN000062353 or TAIR:locus:20136831600115GO_CentralGO_REF:0000033

GO_REF:0000033
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