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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306696
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc10
Name: ATP binding cassette subfamily C member 10
Acc ID: CHEBI:52172
Term: nilotinib
Definition: A carboxamide that has formula C28H22F3N7O.
Chemical ID: MESH:C498826
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc10multiple interactionsISOABCC10 (Homo sapiens)6480464CTDnilotinib inhibits the reaction [ABCC10 protein results in decreased abundance of and results in increased secretion of Paclitaxel]; nilotinib inhibits the reaction [ABCC10 protein results in decreased susceptibility to Paclitaxel]; nilotinib inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine]PMID:19841739
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