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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306565
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map3k5
Name: mitogen-activated protein kinase kinase kinase 5
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k5increases expressionISOMap3k5 (Mus musculus)6480464CTDPalmitic Acid results in increased expression of MAP3K5 proteinPMID:34678374
Map3k5multiple interactionsISOMap3k5 (Mus musculus)6480464CTDcarnosol inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]; PRDX3 protein inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]; PRDX3 protein promotes the reaction [carnosol inhibits the reaction [Palmitic Acid results in increased expression of MAP3K5 protein]]PMID:34678374
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