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GENE - TERM ANNOTATION REPORT

RGD ID: 1306516
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fras1
Name: Fraser extracellular matrix complex subunit 1
Acc ID: GO:0043588
Term: skin development
Definition: The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
Definition Source(s): GOC:jl, UBERON:0002097
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fras1acts_upstream_of_or_withinISOFras1 (Mus musculus)1624291RGDMGI:2667194 MGI:5463442 PMID:17596926 PMID:23469164

PMID:17596926 PMID:23469164
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