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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306468
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Acc ID: CHEBI:53556
Term: toluene 2,4-diisocyanate
Definition: A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring.
Chemical ID: MESH:D014051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3cgincreases expressionISOPik3cg (Mus musculus)6480464CTDToluene 2,4-Diisocyanate results in increased expression of PIK3CG proteinPMID:33711354
Pik3cgmultiple interactionsISOPik3cg (Mus musculus)6480464CTDIC 87114 inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of PIK3CG protein]; N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of PIK3CG protein]PMID:33711354
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