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GENE - TERM ANNOTATION REPORT

RGD ID: 1305982
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ciao3
Name: cytosolic iron-sulfur assembly component 3
Acc ID: GO:0097361
Term: cytosolic [4Fe-4S] assembly targeting complex
Definition: A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in the cytoplasm and nucleus. In humans it consists of MMS19, CIAO1, CIAO2A/CIAO2B, CIAO3. MMS19, CIAO1 and CIAO2A/CIAO2B form a tight 'core' complex, whereas CIAO3 is an 'external' component of this complex.
Definition Source(s): PMID:23585563, PMID:23891004, PMID:34660592
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ciao3part_ofISOCIAO3 (Homo sapiens)1624291RGD PMID:22678361 PMID:22678362 PMID:23585563

PMID:22678361 PMID:22678362 PMID:23585563
Ciao3part_ofIEAUniProtKB:Q9H6Q4 or ensembl:ENSP000002515881600115EnsemblGO_REF:0000107

GO_REF:0000107
Ciao3part_ofIBAPANTHER:PTN000177496 or UniProtKB:Q9H6Q41600115GO_CentralGO_REF:0000033

GO_REF:0000033
Ciao3part_ofISSUniProtKB:Q9H6Q41600115UniProtGO_REF:0000024

GO_REF:0000024
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