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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305633
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rrp1b
Name: ribosomal RNA processing 1B
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rrp1bdecreases expressionISORrp1b (Mus musculus)6480464CTDValproic Acid results in decreased expression of RRP1B mRNAPMID:19136453
Rrp1bdecreases methylationISORRP1B (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of RRP1B genePMID:29154799
Rrp1bincreases expressionISORRP1B (Homo sapiens)6480464CTDValproic Acid results in increased expression of RRP1B mRNAPMID:23179753
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