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GENE - TERM ANNOTATION REPORT

RGD ID: 1305619
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ndufab1
Name: NADH:ubiquinone oxidoreductase subunit AB1
Acc ID: GO:0005747
Term: mitochondrial respiratory chain complex I
Definition: A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
Definition Source(s): GOC:mtg_sensu, ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndufab1located_inISONDUFAB1 (Homo sapiens)1624291RGD PMID:28844695

PMID:28844695
Ndufab1part_ofISONDUFAB1 (Homo sapiens)1624291RGD PMID:12611891 PMID:27626371

PMID:12611891 PMID:27626371
Ndufab1part_ofIBAFB:FBgn0011361 or PANTHER:PTN001074652 or UniProtKB:O14561 or UniProtKB:P525051600115GO_CentralGO_REF:0000033

GO_REF:0000033
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