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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305571
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cnnm4
Name: cyclin and CBS domain divalent metal cation transport mediator 4
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cnnm4affects methylationISOCNNM4 (Homo sapiens)6480464CTDValproic Acid affects the methylation of CNNM4 genePMID:29501571
Cnnm4increases expressionISOCNNM4 (Homo sapiens)6480464CTDValproic Acid results in increased expression of CNNM4 mRNA; Valproic Acid results in increased expression of CNNM4 proteinPMID:24935251 PMID:29154799 PMID:29501571
Cnnm4increases methylationISOCNNM4 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of CNNM4 genePMID:29154799
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