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GENE - TERM ANNOTATION REPORT

RGD ID: 1305520
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aak1
Name: AP2 associated kinase 1
Acc ID: GO:0035612
Term: AP-2 adaptor complex binding
Definition: Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
Definition Source(s): GOC:BHF, PMID:12221107, PMID:15728179, PMID:21097499
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aak1enablesISOAAK1 (Homo sapiens)1624291RGD PMID:17494869

PMID:17494869
Aak1enablesIEAUniProtKB:Q2M2I8 or ensembl:ENSP000003864561600115EnsemblGO_REF:0000107

GO_REF:0000107
Aak1enablesIBAPANTHER:PTN000539992 or Aak1 (Rattus norvegicus) or UniProtKB:Q2M2I81600115GO_CentralGO_REF:0000033

GO_REF:0000033
Aak1enablesIDA 8553925UniProtPMID:11877461

 
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