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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305471
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atf6
Name: activating transcription factor 6
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf6multiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 protein]]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 protein]]; Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 mRNA]; Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 protein]PMID:31433112
Atf6increases expressionISOATF6 (Homo sapiens)6480464CTDresveratrol results in increased expression of ATF6 proteinPMID:24264887
Atf6multiple interactionsISOATF6 (Homo sapiens)6480464CTDresveratrol inhibits the reaction [arsenic trioxide results in increased expression of ATF6 protein]PMID:25107562
Atf6multiple interactionsISOAtf6 (Mus musculus)6480464CTDResveratrol inhibits the reaction [titanium dioxide results in increased cleavage of ATF6 protein]PMID:31298478
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