GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ube2c | decreases expression | ISO | UBE2C (Homo sapiens) | 6480464 | CTD | Etoposide results in decreased expression of UBE2C mRNA; Etoposide results in decreased expression of UBE2C protein | PMID:17374387 PMID:27129209 | Ube2c | multiple interactions | ISO | UBE2C (Homo sapiens) | 6480464 | CTD | [Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein] | PMID:27129209 | | ||||||||||||||||||||||
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