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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305355
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col4a4
Name: collagen type IV alpha 4 chain
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col4a4decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of COL4A4 mRNAPMID:32109520 PMID:33387578 PMID:34747641
Col4a4affects expressionISOCol4a4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of COL4A4 mRNAPMID:26377647
Col4a4decreases expressionISOCol4a4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of COL4A4 mRNAPMID:33956508
Col4a4increases expressionISOCOL4A4 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of COL4A4 mRNAPMID:12377990
Col4a4increases expressionISOCol4a4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of COL4A4 mRNAPMID:27562557
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