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GENE - TERM ANNOTATION REPORT

RGD ID: 1305211
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lipt2
Name: lipoyl(octanoyl) transferase 2
Acc ID: DOID:9000184
Term: Ventricular Fibrillation
Definition: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Definition Source(s): MESH:D014693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lipt2 ISOLIPT2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ventricular fibrillationPMID:11207363 PMID:12414843 PMID:14504341 PMID:15037716 PMID:15212652 PMID:16449802 PMID:17395131 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532
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