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GENE - TERM ANNOTATION REPORT

RGD ID: 1304954
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pold2
Name: DNA polymerase delta 2, accessory subunit
Acc ID: GO:0043625
Term: delta DNA polymerase complex
Definition: A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
Definition Source(s): GOC:jl, ISBN:0198547684, PMID:11205330, PMID:12403614
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pold2 ICGO:00038872307013RGD  
Pold2 IDA 729526RGD  
Pold2located_inISOPOLD2 (Homo sapiens)1624291RGD PMID:12403614

PMID:12403614
Pold2part_ofISOPOLD2 (Homo sapiens)1624291RGD PMID:11595739 PMID:22465957

PMID:11595739 PMID:22465957
Pold2part_ofISOPold2 (Mus musculus)1624291RGD MGI:6383350 PMID:11595739

MGI:6383350 PMID:11595739
Pold2located_inISOComplexPortal:CPX-20971600115ComplexPortalGO_REF:0000114

GO_REF:0000114
Pold2part_ofIBAFB:FBgn0027903 or MGI:1097163 or PANTHER:PTN000045936 or PomBase:SPAC27E2.05 or Pold2 (Rattus norvegicus) or UniProtKB:P49004 or UniProtKB:P490051600115GO_CentralGO_REF:0000033

GO_REF:0000033
Pold2part_ofIEAARBA:ARBA000288851600115UniProtGO_REF:0000117

GO_REF:0000117
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