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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304849
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atad2
Name: ATPase family, AAA domain containing 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atad2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ATAD2 mRNAPMID:32109520
Atad2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ATAD2 mRNAPMID:34747641
Atad2affects expressionISOATAD2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of ATAD2 mRNAPMID:22574217
Atad2affects expressionISOAtad2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ATAD2 mRNAPMID:21570461 PMID:24680724
Atad2decreases expressionISOATAD2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ATAD2 mRNAPMID:20106945 PMID:21632981 PMID:21802500
Atad2multiple interactionsISOAtad2 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ATAD2 mRNAPMID:25975270
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