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GENE - TERM ANNOTATION REPORT

RGD ID: 1304749
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lrp6
Name: LDL receptor related protein 6
Acc ID: GO:0061349
Term: planar cell polarity pathway involved in cardiac right atrium morphogenesis
Definition: The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.
Definition Source(s): GOC:dph, GOC:mtg_heart, PMID:19056682
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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