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RGD ID: 1304727
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mtf2
Name: metal response element binding transcription factor 2
Acc ID: GO:0035098
Term: ESC/E(Z) complex
Definition: A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
Definition Source(s): GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
colocalizes_withIBAMGI:MGI:105050, MGI:MGI:1921266, PANTHER:PTN000290242, UniProtKB:O43189, UniProtKB:Q5T6S313792537GO_CentralPMID:21873635

colocalizes_withISORGD:13324591624291RGD (MGI:MGI:4429983, PMID:20144788)

MGI:MGI:4429983, PMID:20144788
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.