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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304620
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rabgap1l
Name: RAB GTPase activating protein 1-like
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rabgap1laffects expressionISORABGAP1L (Homo sapiens)6480464CTDBenzo(a)pyrene affects the expression of RABGAP1L mRNAPMID:21714911
Rabgap1laffects methylationISORABGAP1L (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of RABGAP1L intron; Benzo(a)pyrene affects the methylation of RABGAP1L promoterPMID:27901495 PMID:30157460
Rabgap1ldecreases expressionISORabgap1l (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of RABGAP1L mRNAPMID:15034205 PMID:19770486 PMID:20713471
Rabgap1ldecreases expressionISORABGAP1L (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of RABGAP1L mRNAPMID:20064835 PMID:20106945 PMID:21632981 PMID:22316170 PMID:26238291 PMID:32234424
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