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GENE - TERM ANNOTATION REPORT

RGD ID: 1304562
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tbc1d1
Name: TBC1 domain family member 1
Acc ID: MP:0003059
Term: decreased insulin secretion
Definition: reduction in the production or release of the hormone secreted by beta cells of the pancreas that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids
Definition Source(s): MESH:D06.472.699.587.740.625, RGD:cur
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tbc1d1inducesIMPdiazoxide and glucose and potassium chloride solution150521607RGDcompared to Wild type

 
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