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GENE - TERM ANNOTATION REPORT

RGD ID: 1303239
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnmt3l
Name: DNA methyltransferase 3 like
Acc ID: GO:0071514
Term: genomic imprinting
Definition: The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.
Definition Source(s): PMID:24492710, PMID:31896690, PMID:31965998
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnmt3lacts_upstream_of_or_withinISODnmt3l (Mus musculus)1624291RGD PMID:22723905

PMID:22723905
Dnmt3linvolved_inISODnmt3l (Mus musculus)1624291RGD MGI:3054275 PMID:15318244

MGI:3054275 PMID:15318244
Dnmt3linvolved_inISSUniProtKB:Q9CWR81600115UniProtGO_REF:0000024

GO_REF:0000024
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