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GENE - TERM ANNOTATION REPORT

RGD ID: 1303178
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nanog
Name: Nanog homeobox
Acc ID: GO:0019827
Term: stem cell population maintenance
Definition: The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
Definition Source(s): GOC:mah, ISBN:0878932437
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nanog IEP 9589811RGD  
Nanogacts_upstream_of_or_withinISONanog (Mus musculus)1624291RGDMGI:1924054 PMID:17938240

PMID:17938240
Nanoginvolved_inISONANOG (Homo sapiens)1624291RGD PMID:15108323

PMID:15108323
Nanoginvolved_inISONanog (Mus musculus)1624291RGD MGI:3042348 PMID:15108323 MGI:5905240 PMID:25825768

MGI:3042348 MGI:5905240 PMID:15108323 PMID:25825768
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