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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303119
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgb6
Name: integrin subunit beta 6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgb6decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ITGB6 mRNAPMID:25181051 PMID:30816183 PMID:32528016
Itgb6increases expressionEXP 6480464CTDbisphenol A results in increased expression of ITGB6 mRNAPMID:34947998
Itgb6multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ITGB6 mRNAPMID:36041667
Itgb6increases expressionISOItgb6 (Mus musculus)6480464CTDbisphenol A results in increased expression of ITGB6 mRNAPMID:26063408 PMID:32156529
Itgb6increases methylationISOITGB6 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of ITGB6 genePMID:31601247
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